00:00 Introduction 00:13 Dr. Lee presents 15:50 Q&A Overview Dr. Lee discusses recent advances in radiation oncology at City of Hope. Key developments include advanced radiotherapy devices, integration of imaging and artificial intelligence, and comprehensive cancer care. These advancements reflect City of Hope's commitment to staying at the forefront of radiation oncology, utilizing state-of-the-art technologies to improve cancer treatment outcomes. ==== About the Prostate Forum ====== Prostate Cancer? You are not alone. The Prostate Forum of Orange County (prostateforum.org) is an all- volunteer organization that has been providing support to prostate cancer patients for more than thirty years. Our goal is to listen, to inform, and to educate, so that people learn to advocate for themselves and become active collaborators with their medical teams in managing their own treatment. The Forum hosts monthly online support meetings (via Zoom) on the second and fourth Tuesday of most months, beginning at 5:00 pm Pacific Time. At the Newly Diagnosed Group, every 2nd Tuesday at 5:00 pm Pacific Time, get help understanding your Prostate Cancer diagnosis. Learn what it means. Talk about your options. At the Advanced/Recurrent Group Group every 4th Tuesday, beginning at 5:00 pm Pacific Time, share your concerns and experiences, and find out what other Prostate Cancer warriors are saying and thinking. Learn about resources, advances, and breakthroughs - advanced treatment options are improving all the time. Monthly Presentations Experts in the treatment and management of Prostate Cancer share their knowledge and experience with us on the fourth Thursday of most months. All meetings are free and are open to anyone affected by prostate cancer – patients, family, friends. Visit the Prostate Forum website: prostateforum.org to: • Register to receive notices of meetings • Advocate for yourself: learn the language of prostate cancer. • Find resources for learning and treatment • Explore a library of a hundreds of expert presentations Our website address is: www.prostateforum.org

Dr. Kishan speaks about emerging technologies and promising developments. He focuses on SBRT (MRI-guided radiation) advances, MIRAGE early results (the 2023 publication — two-year results coming this fall), issues with ViewRay, and the next frontier, e.g., the newly opened HEATWAVE trial. 00:00 Introduction 00:30 Dr. Kishan - Update on SBRT 22:00 Q&A 27:00 About Prostate Forum ========== Prostate Cancer? You are not alone. The Prostate Forum of Orange County (prostateforum.org) is an all- volunteer organization that has been providing support to prostate cancer patients for more than thirty years. Our goal is to listen, to inform, and to educate, so that people learn to advocate for themselves and become active collaborators with their medical teams in managing their own treatment. The Forum hosts monthly online support meetings (via Zoom) on the second and fourth Tuesday of most months, beginning at 5:00 pm Pacific Time. At the Newly Diagnosed Group, every 2nd Tuesday at 5:00 pm Pacific Time, get help understanding your Prostate Cancer diagnosis. Learn what it means. Talk about your options. At the Advanced/Recurrent Group Group every 4th Tuesday, beginning at 5:00 pm Pacific Time, share your concerns and experiences, and find out what other Prostate Cancer warriors are saying and thinking. Learn about resources, advances, and breakthroughs - advanced treatment options are improving all the time. Monthly Presentations Experts in the treatment and management of Prostate Cancer share their knowledge and experience with us on the fourth Thursday of most months. All meetings are free and are open to anyone affected by prostate cancer – patients, family, friends. Visit the Prostate Forum website: prostateforum.org to: • Register to receive notices of meetings • Advocate for yourself: learn the language of prostate cancer. • Find resources for learning and treatment • Explore a library of a hundreds of expert presentations Our website address is: www.prostateforum.org

Advancing Precision Medicine: EpiSwitch PSE Prostate Cancer Screening Test Designed to confirm the presence of prostate cancer, the EpiSwitch Prostate Screening test, known as the PSE, confirms the presence of prostate cancer—whether symptoms are present or not. This technological advancement empowers urologists with important information when deciding if a patient should undergo a biopsy or opt for continued monitoring via active surveillance. Sections: 00:00 Introduction 01:00 Dr. Heaton - EpiSwitch 21:20 Q&A The Prostate Forum of Orange County (prostateforum.org) is an all- volunteer organization that has been providing support to prostate cancer patients for more than thirty years. Our goal is to listen, to inform, and to educate, so that people learn to advocate for themselves and become active collaborators with their medical teams in managing their own treatment. The Forum hosts monthly online support meetings (via Zoom) on the second and fourth Tuesday of most months, beginning at 5:00 pm Pacific Time. You are not alone. At the Newly Diagnosed Group, every 2nd Tuesday at 5:00 pm Pacific Time, get help understanding your Prostate Cancer diagnosis. Learn what it means. Talk about your options. Advanced treatment options are improving all the time. Share your concerns and experiences. Find out what other Prostate Cancer warriors are saying and thinking. Learn about resources, advances, and breakthroughs at the Advanced/Recurrent Group Group every 4th Tuesday, beginning at 5:00 pm Pacific Time. Monthly Presentations Experts in the treatment and management of Prostate Cancer share their knowledge and experience with us on the fourth Thursday of most months. All meetings are free, and open to anyone affected by prostate cancer – patients, family, friends. Visit the Prostate Forum website: prostateforum.org to: • Register to receive notices of meetings • Advocate for yourself: learn the language of prostate cancer. • Find resources for learning and treatment • Explore a library of a hundreds of expert presentations COME TALK TO US. WE'VE BEEN THROUGH IT.

What you don't know can hurt you – never more so than following a cancer diagnosis. Private patient advocates find information you need to make decisions about care. Look to them for assistance with doctors, treatments, and insurance coverage. AnnMarie McIlwain, CEO of Patient Advocators, talks to the Advanced/Recurrent Support Group of the Prostate Forum about how patient advocates, whether personal or professional, can bring clarity , effectiveness, and determination to what is often a frightening and confusing time for prostate cancer patients. Prostate Forum of Orange County is a Southern California Prostate Cancer Support Group, with online (Zoom) meetings on the second and fourth Tuesday of most months, beginning at 5:00 p. Pacific Time. Our website address is: www.prostateforum.org

Dr. Lloyd summarizes the current options available for radiation therapy in advanced, metastatic, and recurrent prostate cancers. He also shares information about exciting technologies at the Hoag Family Cancer Institute that are helping patients with prostate cancer at all stages. Prostate Forum of Orange County is a Southern California Prostate Cancer Support Group, with online (Zoom) meetings on the second and fourth Tuesday of most months, beginning at 5:00 p. Pacific Time. Our website address is: www.prostateforum.org

In this update to his presentation last year, Dr. Presant reports on promising results from a clinical trial with white button mushroom tablets to reduce levels of prostate specific antigen in the blood. Prostate Forum of Orange County is a Southern California Prostate Cancer Support Group, with online (Zoom) meetings on the second and fourth Tuesday of most months, beginning at 5:00 p. Pacific Time. Our website address is: www.prostateforum.org